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Linus Pauling Institute Oregon State University Updated in July 2003 by: Jane Higdon, Ph.D
Pigment Cell Melanoma Res 2016
Research Summary IGF-1 LR3 is a recombinant long arginine analog of insulin-like growth factor 1 with a 13 amino acid N-terminal extension that reduces IGF-binding protein affinity, resulting in a ~120-hour half-life versus 15 hours for native IGF-1
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DPP4 consistently impaired insulin signaling at the level of protein kinase B (the so-called Akt) in several primary cell types like adipocytes, skeletal muscle, and VSMC [132]
(en) Valencia E, Hardy G
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